Hypertensionn
Conditions
Interventions
GroupH:HFNC was administered after extubation under deep anesthesia.
Group C:Normal trachea was extubated.
Sponsors
Gansu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Clinically diagnosed hypertension; 2.ASA I-III, aged 18-65 yr, 18<BMI<30kg/m^2; 3. no history of serious brain, liver or kidney diseases; 4. The patients were reviewed by the ethics committee and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with known or estimated difficult airway; 2. History of severe or uncontrolled chronic obstructive pulmonary disease (severity III or IV), severe or uncontrolled bronchial asthma, pulmonary infection, or bronchiectasis; 3. Thoracic deformities and diseases (such as mediastinal and thoracic tumors); 4. Acute coronary syndrome, sustained ventricular tachyarrhythmia (NYHA class III or IV), severe heart disease; 5. Severe neuromuscular diseases; 6. Previous respiratory or periairway surgery (including thyroid surgery).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline characteristics and population;Operation time;Occurrence of vomiting, agitation, hypertension, and tachycardia in patients;Basic vital signs:Heart rate (HR), mean arterial pressure (MAP), oxygen saturation (spo2), tidal volume (VT) and respiratory rate (RR) were measured before extubation (T1), after extubation (T2) and 10min after extubation (T3);Arterial blood gas analysis was performed before surgery, at the time of entering the PACU, and 10min after extubation. PaO2, PaCO2, PH, SaO2, HCO3, and Lac were measured;Other adverse events;Tolerance score, agitation during recovery period and oropharyngeal pain after recovery were evaluated; | — |
Countries
China
Contacts
Public ContactShi Lei
Gansu Provincial People's Hospital
Outcome results
None listed