Pulmonary function after abdominal surgery in elderly patients
Conditions
Interventions
The Suganglucosesodium group (Group S):When the TOF count was 2 after the operation, a single intravenous injection of Sugamosaccharide sodium at a dose of 2 mg/kg was given.
Neostigmine and atropine group (Group N):When the TOF count was 2 after the operation, a single intravenous injection of neostigmine at 0.02 mg/kg+ atropine at 0.01 mg/kg was given.
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 65 2. Regardless of gender 3. ASA I ~ III 4. For patients to undergo abdominal surgery, the estimated operation time is 2 h ~ 4 h
Exclusion criteria
Exclusion criteria: 1. Severe cardiovascular disease 2. Liver and kidney insufficiency 3. Neuromuscular joint disease 4. Morbid obesity (BMI>40) 5. Allergic to the drug involved in the test 6. Patients who have been included in this study are readmitted, or who are participating in other studies, or who refuse to participate in this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function tests: percentage of forced expiratory volume in one second to predicted value (FEV1), forced vital capacity (FVC), arterial oxygen saturation (SaO2), arterial partial pressure of oxygen (PaO2), and carbon dioxide at the end of expiratory time (PETCO2); | — |
Secondary
| Measure | Time frame |
|---|---|
| General information, operation time, anesthesia time, total dose of intraoperative muscle relaxants, time from final muscle relaxations to the end of operation, time from the end of operation to extubation, time with a TOFr of 0.9, time with a TOF count of 2, and duration of stay at PACU; | — |
Countries
China
Contacts
Public ContactRen Yanling
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed