Evaluation and Precision Medication Research on the Use of Doxycycline for the Treatment of Mycoplasma Pneumoniae Pneumonia in Children Under 8 Years of Age

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500110950

Enrollment

Unknown

Registered

2025-10-23

Start date

2025-11-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mycoplasma Pneumoniae Pneumonia

Interventions

Doxycycline treatment group:Doxycycline anti-infection treatment

Eligibility

Sex/Gender

All

Age

No minimum to 8 Years

Inclusion criteria

Inclusion criteria: 1.Mycoplasma pneumoniae pneumonia (MPP) was confirmed according to MP antigen and antibody detection and NGS detection results, and the presence of macrolide resistance genes; 2.Age < 8 years old; 3.All signed off-label informed consent.

Exclusion criteria

Exclusion criteria: 1. Incomplete examination or record of indicators before and after doxycycline administration; 2. Doxycycline treatment duration <=2d; 3. Children who did not agree to receive safe follow-up.

Design outcomes

Primary

Measure	Time frame
Plasma concentration of doxycycline;Body temperature;The number of times fever-reducing drugs were used;Length of stay;Tooth staining and enamel dysplasia;	—

Countries

China

Contacts

Public ContactLufen Duan

Suzhou Municipal Hospital

duanlufen@126.com+86 186 2501 0502

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026