Gynecological diseases such as uterine fibroids, adenomyosis uteri, and cervical cancer
Conditions
Interventions
Tapentadol Group:Immediately after the operation, administer 1mg of Taglidine
Sufentanil Group:At the end of the operation, 10 µ g of sufentanil was intravenously injected
Butorphanol Group:At the end of the operation, 1mg of butorphanol was intravenously injected
Sponsors
The First People’s Hospital of Jingzhou
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.ASA physical status classification ? or ?; 2.Aged 18–65 years; 3.Patients voluntarily undergoing laparoscopic total hysterectomy; 4.No severe cardiovascular or pulmonary diseases;
Exclusion criteria
Exclusion criteria: 1.Chronic pain; 2.History of mental illness; 3.Long-term history of opioid use; 4.Patients with acute or severe bronchial asthma; 5.Hypersensitivity to opioids; 6.Patients with severe hepatic or renal insufficiency; 7.Patients with acute intestinal obstruction; 8.Patients with acute intestinal perforation; 9.Long-term use of anti-anxiety drugs, antipsychotic drugs, or antidepressants;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Ltchy skin;NRS score;Sedation score;Quality of recovery score;Respiratory depression;Disgusting;Vomiting;Incidence of urinary retention; | — |
Countries
China
Contacts
Public ContactLi Tang
The First People’s Hospital of Jingzhou
Outcome results
None listed