Catheter-Related-Bladder Discomfort
Conditions
Interventions
Oliceridine Group(Group A):Intraoperative analgesia with Oliceridine
Sufentanil Group(Group C):Intraoperative analgesia with sufentanil
Sponsors
Deyang People's Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) Physical Status Classification I–III; 2. Age 18–85 years (inclusive); 3. Ability to comprehend study procedures and communicate effectively with investigators preoperatively; 4. Body Mass Index (BMI) 18–28 kg/m²; 5. Clinically assessed intolerance to pain; 6. Scheduled for elective Transurethral Resection of the Prostate (TURP); 7. Voluntary participation with signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergy to Oliceridine Fumarate Injection, Sufentanil Citrate Injection, Remifentanil Hydrochloride for Injection, or their active ingredients; 2. Severe hepatic impairment (Child-Pugh Class B or C); 3. Renal insufficiency (glomerular filtration rate <30 ml/min/1.73 m²); 4. Patients planned for postoperative transfer to intensive care unit (ICU).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of catheter-related bladder discomfort at awakening period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rescue Medication Administration Events;Laryngeal Mask Removal Time and PACU Stay Duration;Severity of CRBD and NRS Pain Scores During Emergence Period;Severity of CRBD and NRS Pain Scores;Adverse reactions; | — |
Countries
China
Contacts
Public ContactXin Wei
Deyang People's Hospital
Outcome results
None listed