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Comparison of the effects of alfentanil and sufentanil on the quality of postoperative recovery in patients undergoing non-beating heart coronary artery bypass grafting

Comparison of the effects of alfentanil and sufentanil on the quality of postoperative recovery in patients undergoing non-beating heart coronary artery bypass grafting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110927
Enrollment
Unknown
Registered
2025-10-22
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Quality of postoperative recovery

Interventions

Group A (alfentanil group):Anesthesia induction was performed using alfentanil at a dose of 25 µg/kg, and the maintenance dose was 1 to 2 µg/kg/h
Group S (sufentanil group):The induction of anesthesia was administered with sufentanil at a dose of 0.3 µg/kg, and the maintenance dose was 0.2 to 0.4 µg/kg/h

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients scheduled to undergo OPCABG in the Cardiac Surgery Department of Hebei Medical University; 2. Age between 18 and 75 years old; 3. Good cognitive function; 4. No severe functional impairment in other organ systems (such as kidney, brain, blood system diseases); 5. ASA grade ?-?; 6. Voluntary to sign the informed consent form; 7. Surgery duration <= 6 hours.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. Severe mental and psychological disorders; 3. History of alcoholism, drug abuse or substance abuse; 4. Presence of a cardiac pacemaker or intra-aortic balloon pump (IABP); 5. Preoperative pulmonary or other infections; 6. Severe preoperative coagulation disorders; 7. Refusal of the patient or family to participate in the study; 8. Opioid dependence; 9. Surgical duration longer than 6 hours.

Design outcomes

Primary

MeasureTime frame
Postoperative mechanical ventilation time; ICU stay time;total dosage of opioid drugs within 24 hours after surgery.;

Countries

China

Contacts

Public ContactHaitao Liu

The Second Hospital of Hebei Medical University

mzlht@sina.com+86 151 3011 9853

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026