Depression
Conditions
Interventions
Monotherapy Group:Paroxetine hydrochloride tablets alone
Combination Therapy Group:Paroxetine hydrochloride tablets along with SWTX capsules
Healthy Control Group:None
Sponsors
Inner Mongolia Autonomous Region Mental Health Center.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meets the diagnostic criteria for depression according to the 10th edition of the International Classification of Diseases (ICD-10); 2. Has not used paroxetine for treatment within the past 2 weeks; 3. Hamilton Rating Scale for Depression (HAMD-24) score >= 21 points; 4. Liver and kidney function, blood routine, and urine routine test results are within the normal range; 5. Age 18–65, any gender; 6. Education level >= 9 years.
Exclusion criteria
Exclusion criteria: 1. Patients with other serious physical illnesses; 2. Laboratory test results are significantly abnormal; 3. Pregnant women or individuals infected with human immunodeficiency virus; 4. Patients with a serious suicidal tendency; 5. Those who have participated in other psychiatric drug clinical trials within the past 4 weeks; 6. Individuals allergic to paroxetine or the components of Sanwei Sandalwood capsules.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction in Hamilton Rating Scale for Depression scores and reduction rate;Blood concentration;Neurotransmitters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in Montgomery and Asberg Depression Rating Scale scores;Gut microbiota; | — |
Countries
China
Contacts
Public ContactTong Lijun
Inner Mongolia Autonomous Region Mental Health Center
Outcome results
None listed