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Clinical efficacy of the combination of mandibular manipulation with anterior repositioning splint in the management of acute anterior disc displacement without reduction

Clinical effect evaluation of the combination of non-surgical manual disc reduction with anterior repositioning splint used in patients with acute anterior disc displacement without reduction

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110907
Enrollment
Unknown
Registered
2025-10-22
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular disorders

Interventions

Observation group:NA

Sponsors

Second Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age <= 35 years, regardless of gender; 2. Acute limited mouth opening with deviation during opening, maximum interincisal opening less than 35 mm, and disease duration less than 3 months; 3. Diagnosis of at least one side with non-reducing anterior disc displacement confirmed by clinical examination and TMJ MRI, and meeting the DC/TMD diagnostic criteria; 4. Reduction of the displaced disc on the affected side achieved through manual rehabilitation; 5. Completion of the entire repositioning splint therapy process and participation in follow-up; 6. Patient willingness to participate in this clinical study.

Exclusion criteria

Exclusion criteria: 1. History of joint cavity injection, splint therapy, or surgical treatment on the affected side; 2. Severe rheumatic diseases, tumors, or other conditions that render the patient unable to tolerate the treatment; 3. Intracranial or cardiac implants that prevent the patient from undergoing MRI examination; 4. The patient is pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
Successful disc reduction rate;

Secondary

MeasureTime frame
Maximum mouth opening(MMO);Pain intensity;joint sound;Follow-up recurrence rate ;Condylar now bone formation rate;

Countries

China

Contacts

Public ContactGao Bo

Second Affiliated Hospital of Zhejiang University School of Medicine

gaobo2015@zju.edu.cn+86 159 8819 0164

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026