Postoperative chronic foot and ankle injury
Conditions
Interventions
Experimental group:Intermittent theta burst stimulation (iTBS) combined with exercise therapy
Control group:Sham intermittent theta burst stimulation combined with exercise therapy
Observation group:None
Self-cross intervention group:iTBS and sham stimulation, with a one-week interval, repeated fNIRS and TMS assessments before and after the intervention
Sponsors
Jiangsu Province (Suqian) Hospital (Suqian First Hospital)
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Unilateral foot and ankle injury, with surgical treatment performed; 2. Age 18–65 years; 3. Postoperative course >= 3 months; 4. No history of other trauma; 5. Signed informed consent and willing to cooperate with assessments and treatment.
Exclusion criteria
Exclusion criteria: 1. Combined severe dysfunction of major organs such as the heart, liver, or kidneys; 2. Combined mental disorder or cognitive impairment, unable to cooperate with the study; 3. Presence of contraindications for TMS or fNIRS (such as intracranial metal implants, history of epilepsy, etc.); 4. Pregnant or breastfeeding women; 5. Currently participating in other clinical trials that may affect the study results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| American Orthopaedic Foot and Ankle Society Ankle-Hindfoot Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Motor Evoked Potential;Resting Motor Threshold;Cortical Silent Period;Interhemispheric Inhibition;Functional near-infrared spectroscopy technology;VAS assessment;Assessment of Ankle Joint Range of Motion;Isokinetic muscle strength test;10 meter walk test; | — |
Countries
China
Contacts
Public ContactXu Rao
Jiangsu Province (Suqian) Hospital (Suqian First Hospital)
Outcome results
None listed