Normal tension glaucoma
Conditions
Interventions
Experimental group:Lycium Barbarum Glycopeptide Tablets
Sponsors
Eye Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients clearly diagnosed with normal-tension glaucoma (NTG); Diagnostic criteria for normal-tension glaucoma:The diagnostic criteria for NTG are: (1) Gonioscopy examination indicates that the entire angle is open; (2) The median of six untreated intraocular pressure (IOP) measurements is 0.7; (2) Inter-eye difference in VCDR > 0.2; (3) Rim width of the optic disc -20 dB; Criteria for determining visual field progression: Visual field progression is determined based on the EMGT criteria for visual field defect progression. Specifically, if, based on two reliable visual field baselines, at least 3 of the same test points show statistically significant deterioration (P < 0.05) compared to baseline in three consecutive visual field tests, visual field progression is recorded; 4. Willingness to receive relevant treatment; 5. Signed informed consent and voluntary participation in this study.
Exclusion criteria
Exclusion criteria: 1. Patients with secondary glaucoma or glaucoma with elevated intraocular pressure; 2. Patients who use other neuroprotective drugs or traditional Chinese medicine treatments on their own, apart from medications for lowering intraocular pressure or medications for underlying diseases (including hypertension, diabetes, etc.); 3. Patients who are preparing for pregnancy, pregnant, or breastfeeding; 4. Patients who cannot attend follow-up visits on time or are unwilling to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in mean visual field defect; | — |
Secondary
| Measure | Time frame |
|---|---|
| Retinal Nerve Fiber Layer Thickness;Visual Field Index;Visual Evoked Potential P100; | — |
Countries
China
Contacts
Public ContactYuanbo Liang
Eye Hospital of Wenzhou Medical University
Outcome results
None listed