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Study on Clinical Outcomes and Neural Mechanisms of Magnetic Seizure Therapy versus Modified Electroconvulsive Therapy in Alleviating Suicidal Ideation in Patients with Major Depressive Disorder

Study on Clinical Outcomes and Neural Mechanisms of Magnetic Seizure Therapy versus Modified Electroconvulsive Therapy in Alleviating Suicidal Ideation in Patients with Major Depressive Disorder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110862
Enrollment
Unknown
Registered
2025-10-22
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Suicidal ideation in depression

Interventions

Magnetic shock therapy group:Magnetic shock therapy

Sponsors

Affiliated Kangning Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. a diagnosis of MDD according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); 2. a baseline score of >=18 on the 24-item Hamilton Depression Scale (HAMD-24); 3. All patients are first-time MST/MECT recipients and have been clinically assessed by their treating psychiatrist as meeting the indications for MECT/MST and judged to be suitable for MECT/MST treatment; 4. Participants must be on a stable dose of a single antidepressant medication for the duration of the trial; 5. Be between 18 and 55 years of age; 6. sign an informed consent form

Exclusion criteria

Exclusion criteria: 1. current or previous organic brain disease or neurological disease; 2. the presence of contraindications to anaesthesia, such as allergy to anaesthetic drugs; 3. Currently taking antiepileptic drugs, benzodiazepines or other drugs that may affect seizure activity; 4. have received MECT, MST, transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), or other neurostimulation treatments within the past 6 months; 5. presence of cochlear implants, pacemakers, other implanted medical devices or intracranial metals; 6. pregnancy or breastfeeding; 7. concurrent participation in another clinical trial; 8. refusal to provide informed consent; 9. Any other circumstances that the investigator considers unsuitable for participation

Design outcomes

Primary

MeasureTime frame
Clinical scale;

Secondary

MeasureTime frame
Electrophysiological indicators;

Countries

China

Contacts

Public ContactChang Yu

Affiliated Kangning Hospital of Ningbo University

272450699@qq.com+86 158 8810 7922

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026