Suicidal ideation in depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. a diagnosis of MDD according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); 2. a baseline score of >=18 on the 24-item Hamilton Depression Scale (HAMD-24); 3. All patients are first-time MST/MECT recipients and have been clinically assessed by their treating psychiatrist as meeting the indications for MECT/MST and judged to be suitable for MECT/MST treatment; 4. Participants must be on a stable dose of a single antidepressant medication for the duration of the trial; 5. Be between 18 and 55 years of age; 6. sign an informed consent form
Exclusion criteria
Exclusion criteria: 1. current or previous organic brain disease or neurological disease; 2. the presence of contraindications to anaesthesia, such as allergy to anaesthetic drugs; 3. Currently taking antiepileptic drugs, benzodiazepines or other drugs that may affect seizure activity; 4. have received MECT, MST, transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS), transcranial alternating current stimulation (tACS), or other neurostimulation treatments within the past 6 months; 5. presence of cochlear implants, pacemakers, other implanted medical devices or intracranial metals; 6. pregnancy or breastfeeding; 7. concurrent participation in another clinical trial; 8. refusal to provide informed consent; 9. Any other circumstances that the investigator considers unsuitable for participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Electrophysiological indicators; | — |
Countries
China
Contacts
Affiliated Kangning Hospital of Ningbo University