Sepsis
Conditions
Interventions
Sponsors
Linyi Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Healthy group: Individuals from hospital health check-up populations, aged >=18 years, with normal results in complete blood count, urinalysis, liver function biochemical markers, kidney function biochemical markers, and myocardial enzyme spectrum. 2. Underlying disease group: Patients aged >=18 years with underlying conditions such as diabetes or cardiovascular/cerebrovascular diseases, but without infection. 3. Infection group: Patients aged >=18 years with underlying conditions such as diabetes or cardiovascular/cerebrovascular diseases, accompanied by infection. 4. Sepsis group: Patients aged >=18 years admitted to our hospital’s intensive care unit with sepsis and underlying conditions such as diabetes or cardiovascular/cerebrovascular diseases.
Exclusion criteria
Exclusion criteria: 1. Pregnancy; 2. Age under 18 years; 3. Patients with hematologic malignancies, HIV infection, autoimmune diseases, or those receiving immunosuppressive therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Myeloid-derived suppressor cells; | — |
Secondary
| Measure | Time frame |
|---|---|
| Immune-related indicators;Prognostic indicators (e.g., mortality rate, incidence of secondary infections, etc.);MDSC Genome Sequencing;Clinical and diagnostic information (e.g., age, sex, weight/BMI [if available], history of underlying diseases, laboratory tests, etc.); | — |
Countries
China
Contacts
Public ContactLi Guohong
Linyi Central Hospital
Outcome results
None listed