Intracranial aneurysms
Conditions
Interventions
Group Lidocaine:1% lidocaine 10ml was injected through the endotracheal tube for drug injection
Group Remifentanil:Remifentanil Target-Controlled Infusion
Sponsors
Huadong Hospital affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients with intracranial aneurysms undergoing interventional surgery under general anesthesia with endotracheal intubation; 2. ASA grade I-II; 3. Age >=18 years old; 4. Single lumen common endotracheal tube was placed; 5. Mallampatti grade I-III; 6. BMI 18-28 kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Difficult intubation is expected or no extubation is expected after operation 2. preoperative communication disorders 3. History of allergy to amide local anesthetics 4. severe liver and kidney dysfunction/cardiovascular disease/nervous system disease 5. History of asthma or airway hypersensitivity 6. Recent respiratory infection/cold 7. High risk of reflux aspiration (pregnancy/obesity/gastrointestinal obstruction/emergency satiety/esophageal obstruction/esophagotracheal fistula/high intracranial pressure/nausea and vomiting/cardia relaxation/critical condition, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of emergence cough from general anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| hemodynamic changes;the incidence and severity of agitation during emergence from general anesthesia;the severity of coughing during emergence from general anesthesia;the time periods from the end of surgery to eye opening;the time periods from the end of surgery to extubation;incidence of laryngeal spasm and postoperative pulmonary complications; | — |
Countries
China
Contacts
Public ContactGu Weidong
Huadong Hospital Affiliated to Fudan University
Outcome results
None listed