Obesity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: Young adults aged 18 to 30 years; 2. Body Mass Index (BMI): BMI >= 28 kg/m^2; 3. Health status: No severe cardiovascular, respiratory, neurological, or other major diseases that may impair exercise capacity; 4. Exercise capacity: Able to safely perform moderate to high-intensity aerobic and resistance exercise; 5. Informed consent: Willing and able to provide written informed consent and committed to completing all assessments and exercise interventions as required by the study; 6. No recent participation in similar studies: Has not participated in any other weight-loss or exercise intervention studies within the past three months.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women: Due to their special physiological needs, such individuals are temporarily excluded from the study. 2. Severe musculoskeletal disorders: Including but not limited to severe arthritis, history of fractures, or muscle diseases, which may impair physical mobility or increase the risk associated with exercise. 3. Severe metabolic disorders: Such as uncontrolled diabetes, hyperthyroidism, or hypothyroidism, which may affect study outcomes. 4. Mental health conditions: Severe depression, anxiety disorders, or other psychiatric illnesses that may compromise participant engagement or the effectiveness of the intervention. 5. Medication effects: Currently using medications that influence body weight, metabolism, or physical performance, such as weight-loss drugs, corticosteroids, or antidepressants. 6. Allergies or intolerance: Allergic or adverse physiological reactions to certain forms of exercise. 7. Non-compliance with study requirements: Individuals who, during initial screening, demonstrate an inability to adhere to the intervention and assessment protocols.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition (whole-body skeletal muscle mass, whole-body fat mass, and whole-body bone mass, etc.);Body morphology(height, body weight, waist circumference, hip circumference, etc.);Skinfold thickness;Blood pressure;Musculoskeletal ultrasound (muscle thickness, subcutaneous fat thickness, etc.);Maximal oxygen uptake;Hepatic steatosis assessed by ultrasonography;Cardiac function;Vascular function;Blood biochemical indicators (lipid profile, blood glucose, insulin, uric acid, hemoglobin, etc.);One-Repetition Maximum;Lower-limb explosive power(vertical jump height, maximal strength, peak power, etc.);1000-meter run (male) / 800-meter run (female);Pull-ups (male) / Sit-ups (female);50-meter run;Sit-and-reach test;Standing long jump;Vital capacity;Physical Activity Readiness Questionnaire;Food Frequency Questionnaire;Eating Behaviors Assessment for Obesity;24-hour dietary recall;Pittsburgh Sleep Quality Index;In-depth interviews;Genomics profiling;Epigenomic profiling;Metabolomics profiling; | — |
Countries
China
Contacts
Beijing Sport University