lung adenocarcinoma bone metastasis
Conditions
Interventions
Case series:None
Sponsors
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients were diagnosed with lung adenocarcinoma by histopathology; (2) Bone metastasis was confirmed by imaging examination (CT, MRI, ECT or PET/CT); (3) Chest CT and hematological examination were performed when lung adenocarcinoma was diagnosed; (4) Patient medical records were complete, including basic information, clinical data, treatment process and follow-up records.
Exclusion criteria
Exclusion criteria: (1) The pathological type of lung cancer is non-adenocarcinoma or the pathological type is undetermined; (2) The lung malignancy is caused by metastasis of other tumors; (3) It is combined with other primary malignant tumors; (4) It is not determined whether bone metastasis occurs; (5) Chest CT and hematological examinations are incomplete; (6) The medical records are seriously missing, there is no follow-up record, and it cannot meet the research needs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival;Living conditions;Machine learning model evaluation index - Area under the receiver operating characteristic curve , AUC;Prediction model evaluation index-Delong test;Prediction model evaluation index - Calibration curves;Prediction model evaluation index - Decision curve analysis, DCA; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gender;Age(years);Hypertension;Diabetes;Antigen identified by monoclonal antibody Ki-67, Ki-67;Epidermal Growth Factor Receptor, EGFR;White Blood Cell Count, WBC;Absolute Neutrophil Count, ANC;Absolute Lymphocyte Count, ALC;Red Blood Cell Count, RBC;Hemoglobin, HGB;Platelet Count, PLT;C-Reactive Protein, CRP;Albumin, ALB;Alkaline Phosphatase, ALP;Lactate Dehydrogenase, LDH;Calcium, Ca;Inorganic Phosphorus, IP;D-Dimer;Neuron-specific enolase, NSE;Cytokeratin 19 fragment antigen211, CYFRA211;Carcinoma embryonic antigen, CEA;Carbohydrate Antigen 19-9, CA19-9;Carbohydrate Antigen 125, CA125;Serum Ferritin, SF;Interleukin-6, IL-6;Cluster of Differentiation 19 positive, CD19+;Absolute CD19-positive T-cell count, CD19+ Count;Absolute CD3-positive T-cell count, CD3+ Count;Absolute CD8-positive T-cell count, CD8+ Count;Maximum diameter;Location;Lesion distribution;Lung lobe distribution;Number of lesions;Ground glass;Lobulation;Spiculation;Vacuole sign;Pleural traction;Rad-score; | — |
Countries
China
Contacts
Public ContactYanping Yang
Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed