Postoperative pain management
Conditions
Interventions
Group O:The patient was given an intravenous self-controlled infusion of a mixture of oxilast 0.2mg/kg and tropisetron 5mg, with a total volume of 100ml, at a rate of 2ml/h. The PCA volume was 2ml, an
Group S:The patient was infused with a 100ml mixture of sufentanil (1 microgram per kilogram) and tropisetron (5 milligrams) through a venous patient-controlled analgesia (PCA) pump at a rate of 2 ml/
Sponsors
Beijing Zhongguancun Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients undergoing oral and maxillofacial surgery under general anesthesia and receiving PCIA postoperatively: 1. Age: 18 - 75 years old, gender not restricted; 2. American Society of Anesthesiologists classification (ASA classification): I - II grade; 3. Body Mass Index (BMI): 18 - 30 kg/m^2; 4. Normal cognitive function; 5. Patients voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergic to the anesthetic drugs used in this study; 2. Has a history of serious diseases in vital organs such as heart, liver, brain, lungs, and kidneys, or other medical conditions; 3. Has a history of chronic alcohol abuse, drug abuse, or long-term use of psychotropic drugs; 4. Has participated in other clinical trials as a subject within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative resting pain;Postoperative chewing pain;Mean arterial pressure;Heart rate;Respiratory rate;Oxyhemoglobin saturation;The satisfaction of patients;Modified dental anxiety scale;Recovery of analgesic effect frequency;Presence of airway obstruction; | — |
Countries
China
Contacts
Public ContactJin Yue
Beijing Zhongguancun Hospital
Outcome results
None listed