COPD
Conditions
Interventions
Experimental Group:Grononium bromide formoterol inhalation aerosol ,Twice a day
Control group:Tiotropium bromide powder aerosol inhalation aerosol 18 µ g,once a day
Sponsors
Zitong County People's Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed with COPD in accordance with the guidelines of the Global initiative for chronic obstructive pulmonary Disease, aged 40 years or older,<= 80 years old (2) There was no history of acute exacerbation of COPD in the year prior to the visit, or the acute exacerbation occurred once but was relieved without hospitalization (3) Patients can cooperate with pulmonary function tests and complete CAT scores and mMRC questionnaires (4) COPD Group B 10 points <= CAT score < 20 points; (5) Comply with the requirements of the ethics committee, sign the informed consent form, voluntarily use the drug and accept follow-up observation (6) Initial treatment patients; No maintenance bronchodilator treatment was received from 30 days before screening to the first study treatment period
Exclusion criteria
Exclusion criteria: (1) Make a clear diagnosis of asthma patients (2) Patients with significant respiratory diseases other than COPD (3) Patients with other clinically significant uncontrolled diseases (such as severe heart disease, severe hypertension, etc.);Women who are pregnant, breastfeeding or planning to become pregnant during the study period (4) Those who are known or suspected of being allergic to any 2 receptor agonists, M receptor blockers, or investigational drugs; (5) Unhealed oral diseases, such as oral ulcers, oral mucosal damage, oropharyngeal candidiasis, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FEV1; | — |
Secondary
| Measure | Time frame |
|---|---|
| FVC;mMRC;CAT;SPO2;Increase the number of people;Adverse events; | — |
Countries
china
Contacts
Public Contactlin yang
Zitong County People's Hospital
Outcome results
None listed