Parkinson's disease
Conditions
Interventions
Gold Standard:The 2017 Movement Disorder Society Progressive Supranuclear Palsy (PSP) Study Group Diagnostic Criteria?The 2015 Movement Disorder Society (MDS) Diagnostic Criteria for Parkinson's Disea
Index test:MDS UPDRS I-IV scales
Sponsors
Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1Progressive Supranuclear Palsy (PSP) Group: (1) Patients diagnosed with definite or probable PSP according to the 2017 Movement Disorder Society PSP Study Group diagnostic criteria; (2) Participants aged 18 to 80 years (inclusive of boundary values), without limitation of sex; (3) Consent to undergo research-related evaluations and tests, and sign the informed consent form. 2Parkinson's Disease (PD) Group: (1) Patients diagnosed with definite Parkinson's disease according to the 2015 Movement Disorder Society (MDS) diagnostic criteria for Parkinson's disease; (2) Early-stage PD patients with a Hoehn-Yahr staging score of <= 2.5, and mid-to-late-stage PD patients with a Hoehn-Yahr staging score of 3-5; (3) Participants aged 18 to 80 years (inclusive of boundary values), without limitation of sex; (4) Consent to undergo research-related evaluations and tests, and sign the informed consent form. 3Healthy Control Group: (1) Participants aged 18 to 80 years (inclusive of boundary values), without limitation of sex; (2) Consent to undergo research-related evaluations and tests, and sign the informed consent form; (3) Denial of any other neurological diseases.
Exclusion criteria
Exclusion criteria: 1?Severe cognitive dysfunction, precluding the ability to complete the assessment paradigm. 2?Patients with significant organ failure (e.g., cardiac, pulmonary, hepatic, renal), malignancies, unstable medical conditions, or other severe internal medical diseases. 3?Individuals with severe behavioral issues or psychiatric disorders. 4?Inability to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnostic Odds Ratio;Positive Predictive Value;Specificity;Accuracy;Negative Predictive Value;Sensitivity; | — |
Countries
China
Contacts
Public ContactJennifer
Beijing Tiantan Hospital, Capital Medical University
Outcome results
None listed