Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Acute ischemic stroke was confirmed by head CT or MRI; (2) The last normal time interval to the hospital was more than 4.5 hours; (3) Occlusion of large and medium vessels was confirmed by head CTA or MRA: internal carotid artery (ICA) , middle cerebral artery (MCA M 1/M 2/M 3) , anterior cerebral artery (ACA A1/A2) , basilar artery (BA) , vertebral artery (VA) , and posterior cerebral artery (PCA P1/P2); (4) Written informed consent was given by the patient or family member.
Exclusion criteria
Exclusion criteria: (1) Intracranial hemorrhage was confirmed by CT or MRI; (2) Follow-up was not expected to be completed; (3) Patients deemed unsuitable by the investigators were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 90-day mRS;Incidence of symptomatic intracranial hemorrhage (sICH) within 48h; | — |
Secondary
| Measure | Time frame |
|---|---|
| 90-day EQ-5D scale score;Incidence of non-symptomatic intracranial hemorrhage (non sICH) within 48h;NIHSS score at 5-7 days of onset;Incidence of non-intracranial hemorrhage complications;Incidence of non-hemorrhagic serious adverse events; | — |
Countries
China
Contacts
First Affiliated Hospital of Nanchang University