Upper respiratory tract infections and influenza
Conditions
Interventions
Observer group (Compound Paracetamol and Methylephedrine Oral Solution):None
Control group (Pediatric Paracetamol, Atificial Cow-bezoar and Chlorphenamine Maleate Granules):None
Control group (Compound Paracetamol and Dextromethorphan Syrup):None
Control group (Paracetamol,Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide for Suspension):None
Sponsors
Jiangxi Provincial Children's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 15 Years
Inclusion criteria
Inclusion criteria: 1.The clinical diagnosis is upper respiratory tract infection or influenza; 2.The prescription contains Compound Paracetamol and Methylephedrine Oral Solution or Pediatric Paracetamol, Atificial Cowbezoar and Chlorphenamine Maleate Granules or Paracetamol,Pseudoephedrine Hydrochloride and Dextromethorphan Hydrobromide or Compound Paracetamol and Dextromethorphan Syrup; 3 months <= age <= 15 years old; 3.The legal guardian signs the informed consent form, and patients aged 8 years and above also sign the informed consent form themselves.
Exclusion criteria
Exclusion criteria: 1.Based on the researchers' assessment, they determined that the individuals were not suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The disappearance time of single symptoms such as nasal congestion and runny nose, cough, and fever.;The score of the Clinical Global Impression Improvement Scale - Improvement (CGI-I) at the end of taking the medicine.;The changes in the functional dimension and the dimension affecting parents from the baseline on the 1st, 2nd, 3rd, 5th, and 7th after taking the medicine.;The changes in the symptom dimension scores of the Chinese version of the "Canadian Acute Respiratory Disease and Influenza Scale" on the 2nd and 3rd days of medication compared with the baseline.;Recovery rate of upper respiratory tract infection on the 3rd, 5th, and 7th days after taking the medicine;Relief rate of influenza on the 3rd, 5th and 7th days after taking medicine.;Relief time of influenza;On days 2 and 3 of medication, symptom dimension scores of the Chinese version of the "Canadian Acute Respiratory Disease and Influenza Scale" decreased by =50% from baseline.;Recovery time of upper respiratory tract infection;Complete fever reduction time;The disappearance rate of single symptoms such as nasal congestion and runny nose, cough and fever on the 2nd and 3rd days of taking the medicine.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Types and incidence rates of adverse reactions; | — |
Countries
China
Contacts
Public ContactChen Qiang
Jiangxi Provincial Children's Hospital
Outcome results
None listed