Postoperative Nausea and Vomiting (PONV)
Conditions
Interventions
Lidocaine group:Lidocaine was administered during both the induction and maintenance phases of anesthesia.
Control group:Administer an equivalent dose of normal saline during the anesthesia induction and maintenance phases.
Sponsors
Tongling People's Hospital, Tongling City, Anhui Province, China
Eligibility
Sex/Gender
Female
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18-75 years old; 2. American Society of Anesthesiologists (ASA) classification < IV; 3. No serious heart or lung diseases, liver or kidney dysfunction, neurological diseases, or history of lidocaine allergy, etc.
Exclusion criteria
Exclusion criteria: 1.The operation duration is less than 1 hour or longer than 2 hours. 2. Allergic to lidocaine or other anesthetic drugs; 3. Recent use of drugs that affect intracranial pressure or gastrointestinal function; 4. The presence of eye diseases or a history of surgery affects the measurement of the diameter of the optic nerve sheath; 5. Pregnant or lactating women, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Nausea and Vomiting (PONV);Optic nerve sheath diameter; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic indicators (such as heart rate, blood pressure, etc.;The postoperative recovery of the patient (such as the time of first exhaust, length of hospital stay, etc.);Dosage of anesthetic drugs; | — |
Countries
China
Contacts
Public ContactHao Chen
Tongling People's Hospital
Outcome results
None listed