Diabetic Kidney Disease
Conditions
Interventions
Healthy people group:None
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for diabetic nephropathy: (1) Clear diagnosis of diabetes: Meeting the WHO diagnostic criteria for diabetes (fasting blood glucose >=7.0 mmol/L, 2-hour postprandial blood glucose >=11.1 mmol/L, or HbA1c >=6.5%). The disease course is >=5 years (type 1 diabetes) or screening is conducted immediately upon diagnosis (type 2 diabetes). (2) Evidence of renal damage: Albuminuria: Random urine UACR >=30 mg/g (or >=30 mg/24h), lasting for more than 3 months, and with at least 2 positive repeated tests within 3-6 months. Decreased renal function: eGFR<60 ml·min?¹·1.73m?² for more than 3 months (calculated by the MDRD formula); 2. Inclusion criteria for healthy individuals: No abnormalities in blood biochemical indicators such as liver and kidney functions in physical examinations within one year.
Exclusion criteria
Exclusion criteria: 1.Exclusion criteria for participants with diabetic nephropathy: Lack of self-decision-making ability; Chronic kidney disease not caused by diabetes. 2.Exclusion criteria for healthy participants: Abnormal liver and kidney functions and blood routine indicators during physical examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Key genes in calcium metabolism; | — |
Countries
China
Contacts
Public ContactYuan Lin
Peking University Shenzhen Hospital
Outcome results
None listed