Skip to content

A single-center, randomized, single-blind clinical trial of liposomal bupivacaine in postoperative transversus abdominis plane block analgesia in abdominal surgery

A single-center, randomized, single-blind clinical trial of liposomal bupivacaine in postoperative transversus abdominis plane block analgesia in abdominal surgery

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110689
Enrollment
Unknown
Registered
2025-10-17
Start date
2025-06-06
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain

Interventions

Sponsors

Tianjin First Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Any gender, 18-65 years old; 2. Patients undergoing proposed abdominal surgery; 3. American Society of Anesthesiologists (ASA) physical status I to III; 4. Willing to sign an informed consent form, participate in the study, and complete all follow-up visits.

Exclusion criteria

Exclusion criteria: 1. History of allergy to local anesthetics; 2. Past history of dementia, psychosis, or other central nervous system disorders; 3. History of chronic pain or taking opioids and other analgesic drugs; 4. Contraindications to nerve block, including infection at the puncture site and severe coagulation disorders; 5. Chronic use of analgesic medications or known abuse of alcohol, drugs, or narcotics; 6. Concomitant with other conditions that may preclude enrollment, such as breastfeeding, pregnancy, neoplasia, and severe disability; 7. Those who refuse to participate or are unable to communicate; 8. Concurrent enrollment in other clinical trials.

Design outcomes

Primary

MeasureTime frame
NRS score;

Secondary

MeasureTime frame
Restore Quality Rating Sheet (QoR-15);Postoperative agitation score;Postoperative analgesic drug dosage;Postoperative adverse reaction incidence: nausea, vomiting, skin itching, allergic reactions;Time to extubate offline;Post-anesthesia care unit stay time;

Countries

China

Contacts

Public ContactJia Lili

Department of Anesthesiology, Tianjin First Central Hospital

jialili19880801@163.com+86 131 0205 8301

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026