Low blood pressure
Conditions
Interventions
Group C (cyclopofol group):Cyclopofol 0.5mg/kg is used during anesthesia induction
Group P (propofol group):Propofol 2.0 mg/kg is used for anesthesia induction
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for general anesthesia; 2. Age: 18-65 years old; 3.ASA classification I-III; 4.BMI: 18.5-29.9kg/m ² 5. Informed consent of the patient or their family; 6. Cyclopofol or propofol should be used during anesthesia induction
Exclusion criteria
Exclusion criteria: Patients who have been diagnosed with severe circulatory dysfunction; 2. Patients who are unable to communicate due to cognitive dysfunction before the operation; 3. The use of sedative drugs in the short term before the operation; 4. Use vasoactive drugs in the short term before the operation; 5. There are known contraindications or allergies to the use of cyclopofol/propofol; 6. Combined with severe cardiovascular, respiratory and autonomic neuropathy; 7. Those who are determined by the researchers as not eligible for enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of first intraoperative hypotension;First hypotension value;Type, time and dose of vasoactive drug used for the first time;Time to return to normal blood pressure after the first administration of vasoactive drugs.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate and oxygen saturation for first hypotension;Number of occurrences of intraoperative hypotension;The types of vasoactive drugs used intraoperatively and the total dose of the intervention; | — |
Countries
China
Contacts
Public ContactSun Zhentao
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed