Skip to content

Study on the Analgesic Effect of Bupivacaine Liposomes for Modified Brachial Plexus Upper Trunk Block Combined with Supraclavicular Nerve Block After Shoulder Surgery

Study on the Analgesic Effect of Bupivacaine Liposomes for Modified Brachial Plexus Upper Trunk Block Combined with Supraclavicular Nerve Block After Shoulder Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110669
Enrollment
Unknown
Registered
2025-10-17
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shoulder joint disease

Interventions

M Group:General anesthesia + modified superior brachial plexus block group + supraclavicular nerve block
I Group:General anesthesia + traditional intermuscular groove brachial plexus nerve block group + supraclavicular nerve block

Sponsors

The First People’s Hospital of Jingzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18 to 65 years old, ASA (American Society of Anesthesiologists) grade I to III; 2. Patients who are scheduled to undergo total shoulder arthroplasty or rotator cuff repair surgery; 3. Preoperative cognitive function is normal, and the patient can correctly understand pain rating scales (such as NRS scores); 4. There was no history of chronic pain or long-term use of opioids before the operation

Exclusion criteria

Exclusion criteria: 1.History of allergy to local anesthetics (e.g., bupivacaine, ropivacaine) or liposome components; 2.Severe hepatic or renal insufficiency, coagulation dysfunction; 3.Drug abuse or alcoholism; 4.Preexisting neurological or psychiatric diseases affecting pain perception; 5.Patients requiring additional anesthetic analgesic interventions during surgery;

Design outcomes

Primary

MeasureTime frame
Postoperative 48h NRS score;

Secondary

MeasureTime frame
Incidence of adverse reactions such as phrenic nerve paralysis, nausea and vomiting after surgery;Cumulative dose of analgesics used within 72 hours after surgery;Length of hospital stay;Time and dose of the first postoperative analgesic use;NRS scores at 4, 12, 24, and 72 hours post - PACU extubation;Effect and duration of sensory and motor block;

Countries

China

Contacts

Public ContactTang Li

The First People’s Hospital of Jingzhou

462244408@qq.com+86 716 811 3627

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026