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Effective and safety of endovascular treatment plus best medical management for cerebral venous sinus thrombosis: a retrospective study

Effective and safety of endovascular treatment plus best medical management for cerebral venous sinus thrombosis: a retrospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110663
Enrollment
Unknown
Registered
2025-10-17
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral venous sinus thrombosis

Interventions

Endovascular treatment group:None
Standard Drug Administration group:None

Sponsors

The First Affiliated Hospital,Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age over 18 years; 2. At least one venous sinus thrombosis confirmed by cranial imaging; 3. Pre-onset mRS score < 2.

Exclusion criteria

Exclusion criteria: 1. Cerebellar venous thrombosis accompanied by fourth ventricle obstruction and hydrocephalus; 2. Severe liver and kidney function impairment (ALT/AST elevated to more than 3 times the upper limit of normal, creatinine > 3.0 mg/dL); 3. Presence of systemic hemorrhagic disease; 4. Platelets <100×10^9/L; 5. No anticoagulant or endovascular treatment received after definite diagnosis; 6. Lost to follow-up, unable to obtain functional prognosis data.

Design outcomes

Primary

MeasureTime frame
Modified Rankin Scale score of 0-1 at 90 days;—

Secondary

MeasureTime frame
The NIHSS scores at discharge;The proportions of complete recanalization on first follow-up imaging;—

Countries

China

Contacts

Public ContactXing Shihui

The First Affiliated Hospital of Sun Yat-Sen University

xingshih@mail.sysu.edu.cn+86 20 87755766

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026