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The rehabilitation effect of environmental enrichment-based virtual reality on the patients with mild cognitive impairment and underlying neural mechanism

The rehabilitation effect of environmental enrichment-based virtual reality on the patients with mild cognitive impairment and underlying neural mechanism

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110626
Enrollment
Unknown
Registered
2025-10-16
Start date
2025-04-09
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Conventional cognitive therapy group:According to the cognitive impairment of the patients, conventional cognitive treatment methods were given to them, such as occupational therapy, neuropsychologica
Rich environmental treatment based on virtual reality technology group:According to relevant studies at home and abroad, this research intends to adopt the HTC Vive immersive virtual reality device.
b. Conduct relevant questions and answers regarding the identified animals (to stimulate the patients short-term memory)
c. Point out stationary

Sponsors

China-japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.There is subjective memory decline, and informed sources have confirmed the presence of memory decline symptoms for more than three months. 2. Objective evidence of impairment in one or more cognitive domains; 3. Slight impairment of complex instrumental daily abilities, but maintaining independent daily living skills; 4.MMSE > 24 points, or Montreal Cognitive Assessment (MoCA) =50 years old; 7. Informed consent and willingness to participate in this study.

Exclusion criteria

Exclusion criteria: 1. There were severe symptoms of neurological deficits in the past; 2. Accompanied by mental disorders and severe organ lesions; Combined with tumors, tuberculosis or infectious diseases; 3. Have a history of alcohol dependence or drug dependence; 4. Cognitive decline caused by severe Alzheimer's disease or encephalitis, poisoning, or trauma; 5. Severe anxiety, depression or withdrawal from the experiment halfway.

Design outcomes

Primary

MeasureTime frame
MoCA scale score;

Secondary

MeasureTime frame
MMSE;WMS;Deletion of letters, word recognition and sound recognition;LOTCA;Albert test and Benton three-dimensional structure test;Barthel Index;

Countries

China

Contacts

Public ContactJiang Shan

China-japan Friendship Hospital

landjiang@126.com+86 10 8420 6603

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026