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A prospective randomized controlled study: The effect of bupivacaine and bupivacaine liposomes on postoperative pain after tonsillectomy in adults

A prospective randomized controlled study: The effect of bupivacaine and bupivacaine liposomes on postoperative pain after tonsillectomy in adults

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110624
Enrollment
Unknown
Registered
2025-10-16
Start date
2025-10-16
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic tonsillitis

Interventions

Bupivacaine group:During the operation, the patient was injected with bupivacaine liposome for glossopharyngeal nerve block (through the palatopharyngeal fold approach).
Bupivacaine liposome group:During the operation, bupivacaine was injected into the patient for glossopharyngeal nerve block (through the palatopharyngeal fold approach).
Blank (normal saline) group:During the operation, normal saline was injected into the patient for glossopharyngeal nerve block (through the palatopharyngeal fold approach).

Sponsors

The First Hospital Of Jiaxing
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Due to recurrent acute tonsillitis (with >=6 episodes within a year), peritonsillar abscess (treated with failed puncture, incision and drainage, and/or the use of antibacterial drugs, etc.), and tonsillar hypertrophy causing obvious foreign body sensation in the throat, which hinders breathing and swallowing; 2.The patient's hospital information is complete and the informed consent form has been signed;

Exclusion criteria

Exclusion criteria: 1.History of local anesthetic allergy; 2.Use analgesic drugs within 24 hours before the operation; 3.There are contraindications for surgery such as coagulation dysfunction; 4.There are concurrent systemic immune diseases such as rheumatoid arthritis or major diseases such as tumors; 5.Hypertension, diabetes, malignant tumors and other chronic diseases; 6.Immune deficiency diseases such as AIDS; 7.People with mental illness or mental disorders; 8.Pregnant or lactating women; 9.Other researchers consider patients who are not suitable to participate in this study;

Design outcomes

Primary

MeasureTime frame
Pain score;

Secondary

MeasureTime frame
General postoperative conditions (blood pressure, heart rate, body temperature);Incidence of postoperative adverse events (bleeding, vomiting, etc.);The number of people using analgesic drugs and the dosage;Comfort level at each time point;Evaluation of sleep quality;

Countries

China

Contacts

Public ContactJing Deng

The First Hospital Of Jiaxing

30590471@qq.com+86 573 8208 2937

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026