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The impact of perioperative dexmedetomidine on postoperative pain management and promoting recovery after pancreaticoduodenectomy: A propensity score-matched retrospective cohort study

The impact of perioperative dexmedetomidine on postoperative pain management and promoting recovery after pancreaticoduodenectomy: A propensity score-matched retrospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110621
Enrollment
Unknown
Registered
2025-10-16
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-pancreaticoduodenectomy

Interventions

Patients undergoing pancreaticoduodenectomy:None

Sponsors

The Affiliated Drum Tower Hospital of Nanjing University Medical School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Operation in the form of conventional PD or pylorus-preserving PD (PPPD); 2. aged>=18 year.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. Concurrent resection of the liver or colon; 3. Two surgeries within 1 week; 4. Major data incomplete.

Design outcomes

Primary

MeasureTime frame
Incidence rate of moderate to severe pain within 72 hours postoperatively;Incidence rate of major postoperative complications ;

Secondary

MeasureTime frame
Differences of serum surgical stress and inflammatory markers;Incidence of fever within 3 days;Incidence of PPAP, CRPF, infections, DGE after operation ;Length of hospital stay after operation;Duration of postoperative intravenous analgesia;Duration of postoperative use of therapeutic antibiotic; Time to bowel movement;Hospital costs;

Countries

China

Contacts

Public ContactNi Kun

The Affiliated Drum Tower Hospital of Nanjing University Medical School

lemonk_njumc@hotmail.com+86 158 5058 2823

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026