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Effectives of Fascia Iliac Block Combined with Patient-Controlled Intravenous Analgesia on Postoperative Pain, Sleep, and Anxiety Disorder in Oral Cavity Carcinoma Patients Undergoing Anterolateral Thigh Flap Reconstruction: A Randomized Controlled Trial

Effectives of Fascia Iliac Block Combined with Patient-Controlled Intravenous Analgesia on Postoperative Pain, Sleep, and Anxiety Disorder in Oral Cavity Carcinoma Patients Undergoing Anterolateral Thigh Flap Reconstruction: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110613
Enrollment
Unknown
Registered
2025-10-16
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Interventions

Experimental group:After surgery but while still under maintained anesthesia, ultrasound-guided iliac fascia compartment block was performed, combined with a patient-controlled intravenous analgesia (
Control group:A patient-controlled intravenous analgesia (PCIA) protocol using normal-dose dezocine (0.6 mg/kg)

Sponsors

Hospital of Stomatology, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Subjects voluntarily participate in the study and sign the informed consent form; 2.Male or female, aged 18 to 60 years (inclusive); 3.Scheduled to undergo tumor resection with vascularized free anterolateral thigh (ALT) flap reconstruction.

Exclusion criteria

Exclusion criteria: 1.ASA physical status classification > III; 2.BMI 35 kg/m^2; 3.Difficult airway assessed by an anesthesiologist with =3 years of clinical experience; 4.Allergy to ropivacaine, tramadol, or dezocine; 5.Skin infection at iliac fascia block site or preexisting lower limb muscle weakness; 6.Chronic opioid abuse (>6 months) or alcohol addiction; 7.Preoperative diagnosis of anxiety disorder, bipolar disorder, or other non-cooperative psychiatric conditions; 8.Chronic sleep disorders (>6 months)?.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Scale Score;

Secondary

MeasureTime frame
Hospital Anxiety and Depression Scale Score;Pittsburgh Sleep Quality Index;Sleep quality;Athens Insomnia Scale Score;

Countries

China

Contacts

Public ContactYijin Ou

Hospital of Stomatology, Sun Yat-sen University

ouyj65@mail.sysu.edu.cn+86 20 8387 1483

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026