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A prospective, randomized controlled trial of progestogens for luteal-phase support in IVF-ET

A prospective, randomized controlled trial of progestogens for luteal-phase support in IVF-ET

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110611
Enrollment
Unknown
Registered
2025-10-16
Start date
2025-10-20
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

study group:Luteal-phase support was administered using allylestrenol tablets and dydrogesterone tablets.
control group:Luteal-phase support was provided using progesterone vaginal sustained-release gel and dydrogesterone tablets.

Sponsors

Sichuan Provincial Women and Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Women of reproductive age between 20 and 40 years, undergoing their first IVF-ET treatment, with controlled ovarian stimulation using a gonadotropin-releasing hormone antagonist protocol, and receiving fresh embryo transfer.

Exclusion criteria

Exclusion criteria: Exclusion criteria: uterine factors affecting embryo implantation (such as uterine malformations, submucosal or intramural fibroids, adenomyosis), history of recurrent pregnancy loss, use of donor sperm, preimplantation genetic testing, contraindications to allylestrenol or progesterone gel, and body mass index 28.

Design outcomes

Primary

MeasureTime frame
Live birth rate;

Secondary

MeasureTime frame
Embryo implantation rate;Biochemical pregnancy loss rate;Ongoing pregnancy rate;Early miscarriage rate;Multiple pregnancy rate;

Countries

China

Contacts

Public ContactGong Yan

Sichuan Provincial Women and Children's Hospital

gongyan_496181657@qq.com+86 152 0839 3996

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026