Postoperative Delirium
Conditions
Interventions
Group A:Sufentanil at 0.05 µg/kg/h plus remimazolam at 0.02 mg/kg/h
Group B:Sufentanil at 0.05 µg/kg/h plus remimazolam at 0.04 mg/kg/h
Control group:Sufentanil at 0.05 µg/kg/h
Sponsors
Ganzhou Municipal People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Patients scheduled for elective radical gastrectomy, with an American Society of Anesthesiologists (ASA) physical status classification of I to III. (2) A Mini-Mental State Examination (MMSE) score of greater than 20. (3) Aged between 60 and 70 years, with no restrictions on gender. (4) Body Mass Index (BMI) ranging from 18 to 30 kg/m². (5) Having provided written informed consent for anesthesia.
Exclusion criteria
Exclusion criteria: (1) History of chronic alcoholism, use of analgesic/sedative medications, or drug abuse. (2) Mini-Mental State Examination (MMSE) score <= 20. (3) Pre-existing psychiatric or cognitive disorders. (4) Severe visual or auditory impairment. (5) Known allergy to the study medications. (6) Significant cardiovascular or organ dysfunction. (7) Severe electrolyte disturbances, moderate to severe hypoalbuminemia, or moderate to severe anemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of CAM-positive patients at each time point;VAS pain scores at each time point; | — |
Secondary
| Measure | Time frame |
|---|---|
| Distribution of patients across different Ramsay sedation scores at each time point.;Number of patient-controlled analgesia (PCA) demands;Heart rate, mean arterial pressure SpO2; | — |
Countries
China
Contacts
Public ContactWu Xiaoqin
Ganzhou Municipal People's Hospital
Outcome results
None listed