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To establish and validate a prediction model for chemotherapy-induced nausea and vomiting in patients with liver cancer after interventional therapy

To establish and validate a prediction model for chemotherapy-induced nausea and vomiting in patients with liver cancer after interventional therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110585
Enrollment
Unknown
Registered
2025-10-16
Start date
2025-10-31
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy-induced nausea and vomiting

Interventions

Chemotherapy-related nausea and vomiting group/observation group without chemotherapy-related nausea and vomiting:None

Sponsors

Tianjin Cancer Institute &Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Liver malignant tumor was diagnosed by histological or cytological examination; 2. Age >= 16 years old; 3. Expected survival time >=3 months; 4. There were no obvious abnormalities in liver and kidney function, blood routine and electrocardiogram before treatment. 5. HAIC or TACE interventional therapy was performed; 6. Antiemetic agents were given according to the guidelines and expert consensus on the prevention and treatment of vomiting related to tumor treatment; 7. Be able to communicate with medical staff; 8. Informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1.Currently suffering from intestinal obstruction, with severe digestive tract diseases or a history of such conditions; 2. Concurrent chemoradiotherapy; 3. Combined with brain metastases or other diseases that can lead to increased intracranial pressure; 4. Have a history of mental illness or have recently experienced other major stressful events; 5. Strong opioid drugs have been used within the last week.

Design outcomes

Primary

MeasureTime frame
Chemotherapy-induced nausea and vomiting;Quality of life evaluation;

Secondary

MeasureTime frame
Area under the receiver operating characteristic curve, AUC;Accuracy;Sensitivity;Specificity;

Countries

China

Contacts

Public ContactYongjian Wang

Tianjin Cancer Institute &Hospital

1251210544@qq.com+86 23340123

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026