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Analysis of clinical and imaging results of lateral anterior approach (OLIF) in the treatment of adjacent segment degenerative disease (ASD) after posterior lumbar fusion

Analysis of clinical and imaging results of lateral anterior approach (OLIF) in the treatment of adjacent segment degenerative disease (ASD) after posterior lumbar fusion - OLIF in ASD after lumbar fusion

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110564
Enrollment
Unknown
Registered
2025-10-15
Start date
2025-10-15
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar degenerative disease

Interventions

Group of the lateral anterior approach (OLIF) :None
Group of the posterior transposterior approach (TLIF) :None

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1 Age >= 50 years, diagnosed with lumbar degenerative disease (lumbar disc herniation, lumbar spinal stenosis, spondylolisthesis, etc.); 2 Previous posterior lumbar fusion (PLIF/TLIF/PSF, etc.), with clinical symptoms (low back pain, sciatica, etc.) due to adjacent segment degeneration with radiographic evidence, and revision surgery after ineffective conservative treatment; 3 Revision with OLIF (either anterior alone or combined with short-segment posterior fixation) or TLIF (posterior decompression + interbody fusion with extended fixation) with complete clinical data; 4 Postoperative follow-up of >= 1 year.

Exclusion criteria

Exclusion criteria: 1 Lumbar spine surgery due to non-degenerative conditions (e.g., tumor, infection, trauma, spinal deformity, etc.). 2 Pre-operative severe neurological disease (e.g., spinal cord injury, Parkinson's disease, etc.) or mental disorder. 3 Missing clinical data (e.g., incomplete key surgical records or follow-up data). 4 Death or loss to follow-up during follow-up due to non-lumbar spine causes.

Design outcomes

Primary

MeasureTime frame
Postoperative functional recovery;

Secondary

MeasureTime frame
Basic Information;

Countries

China

Contacts

Public ContactXue Jing

Department of Orthopedics, West China Hospital, Sichuan University

63291605@qq.com+86 135 4121 1401

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026