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A Study on the Cortical Control Mechanisms of Post-Stroke Aphasia and Dysarthria under Natural Conditions

A Study on the Cortical Control Mechanisms of Post-Stroke Aphasia and Dysarthria under Natural Conditions

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110548
Enrollment
Unknown
Registered
2025-10-15
Start date
2025-10-15
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke language impairments encompass aphasia and dysarthria, both of which significantly impact patients' communication abilities and rehabilitation outcomes. Aphasia primarily manifests as deficits in language comprehension, expression, reading, and writing

Interventions

Articulation Disorder Group:None
Healthy control group:None

Sponsors

Shanghai Second Rehabilitation Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Age 18–80 years; 2.Four weeks to 24 months post-stroke; 3.Aphasia group: Meeting the aforementioned diagnostic criteria for aphasia and confirmed through scale assessment; 4.Articulation Disorder Group: Meeting the aforementioned diagnostic criteria for articulation disorders and confirmed through assessment by a speech therapist; 5.Healthy control group: No history of stroke or neurological disorders; normal language and articulation functions; 6.All subjects must have completed at least six years of education and be able to cooperate in completing tasks and assessments. 7.Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.A history of severe neurological or psychiatric disorders; 2.Severe cognitive impairment rendering cooperation impossible; 3.Severe uncorrected visual and hearing impairment; 4.Other researchers deem the situation unsuitable for inclusion in the study.

Design outcomes

Primary

MeasureTime frame
Functional Near-Infrared Spectroscopy,fNIRS;

Secondary

MeasureTime frame
Spoken rate;Communicative Activities of Daily Living-Second Edition,CADL-2;Western Aphasia Battery, WAB;Frenchay Dysarthria Assessment,FDA-2;

Countries

China

Contacts

Public ContactJiayi Xia

Shanghai Second Rehabilitation Hospital

532821681@qq.com+86 177 2148 5860

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026