Pediatric inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis.
Conditions
Interventions
Inflammatory bowel disease (IBD) group:no
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 16 Years
Inclusion criteria
Inclusion criteria: 1. Children aged 0–16 years; 2. Both sexes are eligible; 3. Diagnosed with inflammatory bowel disease (including Crohn’s disease and ulcerative colitis) according to the Porto criteria, with complete documentation of endoscopic, imaging, pathological biopsy, and laboratory test results; 4. Legal guardian(s) of the child must provide written informed consent for participation in the study, commit to adhering to study protocols, and cooperate throughout the entire research process.
Exclusion criteria
Exclusion criteria: 1. Presence of clinically significant abnormalities in hepatic/renal function, neurological, respiratory, or coagulation systems, or unstable vital signs as determined by the investigator; 2. History of other underlying medical conditions; 3. Any other circumstances deemed by the investigator to contraindicate study participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Single-cell transcriptome sequencing; | — |
Secondary
| Measure | Time frame |
|---|---|
| platelet,PLT;pediatric Crohn's disease activity index,PCDAI;C reactive protein,CRP; | — |
Countries
China
Contacts
Public ContactXinqiong Wang
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed