Spinal Cord Injury
Conditions
Interventions
Anterior Surgery Group:Anterior cervical discectomy and fusion (ACDF), anterior cervical corpectomy decompression and fusion (ACCF), and combinations of these procedures.
Posterior Surgery Group:Laminoplasty with or without short-segment internal fixation.
Sponsors
Huashan Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) A clear history of injury; (2) Age 18-70 years; (3) Symptoms and signs of acute cervical spinal cord injury (time from injury to surgery = 3 segments (spinal cord compression segments or spinal cord edema segments); (8) Both surgical options are applicable; (9) The patient or their authorized representative is aware of and has signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Clear contraindications for anterior cervical surgery (developmental spinal canal stenosis, ossification of the posterior longitudinal ligament involving >=3 vertebrae, or CT showing ossification thickness >=5mm, or canal encroachment rate >=50%; or severe osteoporosis with T-score =13°); (3) Cervical bone structural abnormalities; (4) History of previous cervical spine surgery; (5) Severe cardiopulmonary disease unable to tolerate surgery; (6) Combined injuries to other vital organs; (7) Combined psychiatric and neurological disorders affecting subsequent functional evaluation (schizophrenia, Parkinson's disease, Alzheimer's disease, multiple sclerosis, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| American Spinal Injury Association (ASIA) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Operation time;Intraoperative blood loss;Postoperative drainage volume;Postoperative hospitalization days;Surgical related complications;JOA Scores;NDI index;SF-12 scale;Cervical range of motion;C2-7 SVA;Spinal cord hyperintensity in T2WI;Maximum compression degree of spinal cord;Maximum stenosis degree of spinal canal;Internal fixation loosening;Fixed segment not fused;Hinge fracture or re-closure of lamina; | — |
Countries
China
Contacts
Public ContactHongli Wang
Department of Orthopedics, Huashan Hospital, Fudan University
Outcome results
None listed