Thyroid cancer
Conditions
Interventions
R1 group:Continuous intraoperative infusion of rocuronium bromide (3~5µg/kg/min)
R2 group:Intermittent intravenous injection of 1/5 of the induction dose
R3 group:Intermittent intravenous injection of 1/6 of the induction dose
Sponsors
Luwan Branch of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged 18-50 years with ASA classification I-II undergoing radical thyroidectomy
Exclusion criteria
Exclusion criteria: 1. Patients with a history of neuromuscular diseases; 2. Those with a previous recurrent laryngeal nerve injury or vocal cord paralysis; 3. Patients with preoperative liver or kidney dysfunction; 4. Patients identified as allergic to rocuronium bromide; 5. Patients with peripheral neuromuscular disease, a history of forearm or distal limb surgery, or those for whom neuromuscular monitoring cannot be performed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative satisfaction score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in success rates of neural monitoring;Differences in amplitude of neural stimulation signals;Differences in postoperative extubation time and adverse reactions during the recovery period; | — |
Countries
China
Contacts
Public ContactShen Liang
Luwan Branch of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed