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Clinical Efficacy of Ultrasound-Guided Brachial Plexus Block for Manipulative Therapy Combined with Platelet-Rich Plasma Injection in the Treatment of Adhesive Capsulitis of the Shoulder

Clinical Efficacy of Ultrasound-Guided Brachial Plexus Block for Manipulative Therapy Combined with Platelet-Rich Plasma Injection in the Treatment of Adhesive Capsulitis of the Shoulder

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110516
Enrollment
Unknown
Registered
2025-10-15
Start date
2025-10-19
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adhesive shoulder capsulitis

Interventions

Control:Manipulation Under Anesthesia (MUA) of the shoulder
Treated:Manipulation Under Anesthesia (MUA) of the shoulder and PRP injection

Sponsors

The Fourth People's Hospital of Guiyang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Clinically diagnosed with adhesive capsulitis (AC), presenting with shoulder pain and limited active and passive range of motion, particularly noticeable in abduction and external rotation. 2. Active range of motion (AROM) is moderately to severely restricted or nearly impossible to move independently (e.g., shoulder flexion <10°); passive range of motion (PROM) is moderately to severely restricted. 3. Imaging shows features consistent with adhesive capsulitis, with shoulder MRI graded I–II according to Neviaser. 4. Pain visual analog scale (VAS) score =5. 5. Oral nonsteroidal anti-inflammatory drugs (NSAIDs) provide insufficient pain relief, making effective self-directed rehabilitation difficult. 6. The participant voluntarily consents and signs an informed consent form, meeting ethical review requirements.

Exclusion criteria

Exclusion criteria: 1. History of previous shoulder trauma fracture or surgery, or previous intra-articular shoulder injection history. 2. Presence of obvious periarticular tendon calcification, making manual loosening inappropriate. 3. Combined active tuberculosis, tumors, hematological diseases, severe cardiovascular or cerebrovascular diseases, or coagulation disorders. 4. Confirmed history of thyroid disease (relative contraindication for brachial plexus anesthesia) or other anesthesia contraindications. 5. Imaging indicates rotator cuff tear (e.g., supraspinatus tendon). 6. Refusal to accept brachial plexus block anesthesia or refusal of related treatment and follow-up.

Design outcomes

Primary

MeasureTime frame
visual amalogue scale,;

Secondary

MeasureTime frame
Oxford Shoulder Score;

Countries

China

Contacts

Public ContactYang Shuifen

The Fourth People's Hospital of Guiyang

565979411@qq.com+86 177 8559 5472

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026