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Intergenerational Effects of Gestational Obstructive Sleep Apnea Syndrome: Multi-Omics Mechanism Analysis

Intergenerational Effects of Gestational Obstructive Sleep Apnea Syndrome: Multi-Omics Mechanism Analysis and Risk Early-Warning Model Construction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500110510
Enrollment
Unknown
Registered
2025-10-14
Start date
2025-10-20
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gestational Obstructive Sleep Apnea Syndrome

Interventions

Non-OSAS group:None
OSAS group:None

Sponsors

Binzhou Medical University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18 and 45 years; 2. Voluntarily agree to provide blood samples during initial diagnosis and/or follow-up visits, as well as umbilical cord blood and placental tissue at delivery, and provide written informed consent for study participation.

Exclusion criteria

Exclusion criteria: 1. Multiple gestation or fetal malformation; 2. Regular smoking, regular alcohol consumption, or irregular diet/sleep patterns; 3. Prior diagnosis of OSAS or regular CPAP treatment before pregnancy/study enrollment (defined as device usage >=21 days/30 days with >=4 hours/night); 4. Clinically unstable conditions (e.g., subjects with significant cardiopulmonary comorbidities or severe psychiatric disorders); 5. Other sleep disorders.

Design outcomes

Primary

MeasureTime frame
Differential expression of biomarkers;—

Countries

China

Contacts

Public ContactJingyu Wang

The Affiliated Hospital of Binzhou Medical University

lovewangmoran@126.com+86 150 5436 6686

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026