Acute pain after thoracic surgery
Conditions
Interventions
Group A:The TPVB block space is the thoracic paravertebral space corresponding to the surgical incision and the adjacent upper space
Group:The TPVB block space is the thoracic paravertebral space corresponding to the surgical incision and the adjacent downward space
Group C:The TPVB block space is the upper and lower space adjacent to the thoracic paravertebral space corresponding to the surgical incision, and the space where the surgical incision sits is not inj
Sponsors
Beijing Chest Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. ASA classification I-III, age 18-70, gender is not limited; 2. Patients undergoing single-port thoracoscopic surgery, with lung wedge, lung segment and lobectomy;
Exclusion criteria
Exclusion criteria: 1. Patients who are not treated with a multimodal analgesic regimen (thoracic paravertebral block, intravenous analgesic pump); 2. Patients with contraindications to paravertebral block, such as a history of thoracic spine injury, anatomical variation of thoracic vertebral segments, infectious diseases in the skin tissue at the injection site, and abnormal coagulation function; 3. Patients with persistent chronic pain before surgery; 4. Patients with opioid and alcohol dependence; 5. Patients with previous allergy to local anesthetics; 6. morbidly obese patients (BMI>40 kg/m^2); 7. Patients with severe cardiovascular and cerebrovascular diseases; 8. Patients who are unable to express themselves verbally or do not respond to pain scores; 9. Pregnant or lactating females, those who have a birth plan within half a year, and who are unwilling or unable to take effective contraceptive measures 10. Patients who voluntarily request to withdraw from the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AUC area of cough NRS score 0-48 h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative 4, 24, and 48h NRS scores;Opioid consumption at the end of the operation, 24 hours, and 48 hours after surgery;Patient's Ramsay score in PACU;QoR-15 score at 48h postoperatively;The number of effective compressions of the analgesic pump and the postoperative analgesic remediation;Perioperative blood pressure, heart rate, blood oxygen;Duration of indwelling drain and length of hospital stay;Postoperative complications;Intraoperative changes in blood glucose;Postoperative CRP content; | — |
Countries
China
Contacts
Public ContactLiu Tao
Beijing Chest Hospital Affiliated to Capital Medical University
Outcome results
None listed