1. Malignant lesions: Main types: Peripheral lung cancer, among which the most common subtypes are lung adenocarcinoma and lung squamous cell carcinoma. One of the goals of this study is to distinguish between these two subtypes. 2. Benign lesions: Infectious/inflammatory lesions: Such as pulmonary tuberculosis ball, inflammatory pseudotumor, organizing pneumonia, etc. Benign tumors: Such as pulm
Conditions
Interventions
Gold Standard:The establishment of the gold standard relies on lung lesion tissues obtained from patients through surgical resection or needle biopsy. Diagnoses are independently evaluated in accordan
Index test:1.Data collection method: The use of dual-modal ultrasound imaging, i.e., simultaneous acquisition of conventional grayscale ultrasound (B-mode) images and dynamic sequences of contrast-enh
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged 18 years or older; 2. Having ultrasonic images that can clearly show lung lesions; 3. Patients with pathological results after surgery or lung tumor puncture; 4. Research subjects who have been informed of and consented to the research protocol of this project, and have provided a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with pathologically confirmed malignant tumors metastasized to the lungs from other sites; 2. Patients with poor-quality acquired ultrasonic images; 3. Patients with missing clinical data; 4. ROI delineation failure criteria (any of the following): Dice similarity coefficient (DSC) between two physicians' delineations 2.5 mm; proportion of regions with uneven contrast agent perfusion > 20%; lesion boundary visibility < 70% (such cases need to be recorded separately and the proportion reported).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area under the curve;Recall;Weighted F1;Specificity;Sensitivity;Negative predictive value;Precision;Positive Predictive Value; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brier score;Macro-Averaged Recall; | — |
Countries
China
Contacts
Public ContactShi Yu
Peking University Shenzhen Hospital
Outcome results
None listed