Solid Tumors
Conditions
Interventions
Gold Standard:For tumor samples??, the reference standard in this study is a comprehensive assessment based on ??histopathological diagnosis?? of surgically resected or biopsied specimens, combined wi
Index test:The index tests in this study primarily include optimized multi-gene and pan-cancer NGS detection panels with a machine learning-based mutation interpretation model for solid tumors, as wel
Sponsors
Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Solid Tumor Patients:?? Age over 18 years; underwent tumor resection surgery at our hospital, with tissue samples stored in our institution for = 2 ml, and infected tissue sample weight >= 50 mg; availability of comprehensive clinical and pathological information.
Exclusion criteria
Exclusion criteria: 1. Oncology-related exclusions:?? Patients with metastatic cancer of unknown primary origin; history of previous malignancy; any form of anticancer therapy prior to surgery, including radiotherapy, chemotherapy, neoadjuvant therapy, or immunotherapy; tissue samples archived for >5 years or with tumor content 99%; cases of mixed infection with >= 4 distinct pathogen species identified; recipients of organ transplants or prior allogeneic bone marrow or stem cell transplantation; samples with positive blood culture results but no other evidence of localized infection; any other clinically significant condition deemed by the investigator to make the patient unsuitable for participation in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Agreement;Sensitivity; | — |
Secondary
| Measure | Time frame |
|---|---|
| Specificity;Limit of Detection; | — |
Countries
China
Contacts
Public ContactYu Zhou
Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China
Outcome results
None listed