Thyroid tumor
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age 18-65 years old; 2. Female patients with >=1h and <=4h of surgery, elective general anesthesia to descend thyroid gland lobe or total resection + lymph node dissection; 3. ASA score is grade I or II; 4.18 kg/m^2<BMI<30 kg/m^2 Clearly understood, voluntarily participated in the study, and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with thyroid tumors with an operation time of 4 hours, requiring simple adenolobectomy or complex surgery; 2. ASA score of grade III or above; 3. Patients who are taking any sedatives, opioids or sleep aids; 4. Obese patients with BMI >=30 kg/m^2, pregnant or lactating patients; 5. Allergic or contraindicated to the above-mentioned test drugs such as cyclopol, opioids, remifentanil, etc.; 6. Patients who have participated in other drug clinical trials as subjects in the past 3 months are not suitable for this trial in the opinion of the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40 of POD1; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hospitalization time;Blood pressure, heart rate SpO2;Dosage of antiemetic and analgesic agents used;PACU dwell time;Injection pain and incidence of PONV;Hypotension incidence rate;Cortisol and noradrenaline levels in the blood;Total amount of remifentanil;Decannulation time;RS rating;QoR-40 before surgery and POD2; | — |
Countries
China
Contacts
Xianyang Central Hospital