Gynecological surgery
Conditions
Interventions
Trial group:Administer 15µg/kg of hydromorphine (diluted to 20ml) before surgical skin incision.
Control group:Inject 20 mL of 0.9% sodium chloride injection before the surgical skin incision
Sponsors
Jintang County first People's Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age: 20 -80 years old, BMI(18.5-30kg/m^2); 2. Elective laparoscopic gynecological surgery, anesthesia method: tracheal intubation general anesthesia; 3. Clear and conscious, free from mental disorders, intellectual disabilities or other diseases; 4. ASA classification: Grade I- III; Cardiac function: Grades 1-3.
Exclusion criteria
Exclusion criteria: 1. Combined with functional failure of important organs such as the heart and lungs; 2. Concurrent acute and chronic systemic infections; 3. Allergic to the drugs used in this study; 4. Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stress hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammatory factorsCRP ;Recovery period restlessness score;VAS score;Average blood pressure, HR (heart rate) and SpO2 (blood oxygen saturation);Quality of anesthesia recovery; | — |
Countries
China
Contacts
Public ContactQu Yang
First People's Hospital of Jintang County, Sichuan Province
Outcome results
None listed