Pancreatitis
Conditions
Interventions
intervention group of acute pancreatitis:Conventional therapy plus Compound Leucine Granules (oral, three times daily for 7 days)
Control group of acute pancreatitis:Conventional therapy plus placebo (oral, three times daily for 7 days)
Intervention group of Chronic pancreatitis:Conventional therapy plus Compound Leucine Granules (oral, three times daily for 7 days)
Control group of chronic pancreatitis:Conventional therapy plus placebo (oral, three times daily for 7 days)
Sponsors
The First Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.For patients with mild to moderate acute pancreatitis or chronic pancreatitis in the Hepatobiliary Pancreatic Surgery Department of the First Affiliated Hospital of Harbin Medical University; 2.Two weeks before taking medication, there was no antibiotic treatment and no severe diarrhea; 3.Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe acute pancreatitis; 2.There are serious intestinal diseases such as inflammatory bowel disease (Crohn's disease, ulcerative colitis), intestinal obstruction, intestinal perforation, intestinal cancer, intestinal ischemia, necrotizing enterocolitis and some serious infectious diseases; 3.Individuals with bacteremia, sepsis, and severe abdominal infections; 4.History of using antibiotics, acid suppressants, and other medications within two weeks; 5.Individuals over 65 years old with a high incidence of underlying diseases; 6.Combined with serious physical diseases or organic lesions in the brain, such as severe organ dysfunction of the heart, liver, and kidneys, malignant tumors, etc; 7.Those who are unable to collect feces; 8.Pregnant, perinatal, or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative complications related to pancreatic surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dynamic changes in inflammatory markers;Length of hospital stay and hospitalization costs; | — |
Countries
China
Contacts
Public ContactSun Bei
The First Affiliated Hospital of Harbin Medical University
Outcome results
None listed