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Investigating the Effects of Lower Limb Robotics on Gait and Lower Limb Motor Function in Healthy Subjects Based on Corticomuscular Coupling Principles

Investigating the Effects of Lower Limb Robotics on Gait and Lower Limb Motor Function in Healthy Subjects Based on Corticomuscular Coupling Principles

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110435
Enrollment
Unknown
Registered
2025-10-14
Start date
2025-10-15
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Control Group: Conventional gait training, 30 minutes per session, a total of 1 session.
Intervention Group:Lower Limb Robot-Assisted Training: Patients received gait training using the Lokomat robotic gait orthosis. According to the predefined trial protocol, the initial body weight su
the initial walking speed was set between 1.0 and 2.0 km/h
and the initial guidance force was set at 100%, subsequently reduced based on individual gait characteristics to a minimum of 10%. Each robot-assisted session lasted 30 minutes and was performed once.

Sponsors

The First Rehabilitation Hospital of Shanghai
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Normal or corrected-to-normal vision; 2. Aged between 18 and 80 years; 3. Absence of gait disorders and free from impairments of the limbs.

Exclusion criteria

Exclusion criteria: 1. History of any neurological or physical disorders; 2. History of any psychological or psychiatric disorders; 3. History of lower limb fracture or related surgical procedures; 4. Prior experience with robotic-assisted gait training.

Design outcomes

Primary

MeasureTime frame
Oxygenated HemoglobinSignals Measured by Functional Near-Infrared Spectroscopy;Surface electromyography indicator;Kinematic and kinetic parameters (gait spatiotemporal variables, lower limb joint angles, ground reaction forces, and lower limb joint moments, etc.);Functional Near-Infrared Spectroscopy-Based Brain Functional Connectivity Metrics;

Secondary

MeasureTime frame
Balance Platform Parameters;

Countries

China

Contacts

Public ContactWu Xuejiao

The First Rehabilitation Hospital of Shanghai

wxj11j@163.com+86 21 6543 2021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026