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Multidimensional Frailty-Symptom Interaction Mechanisms in Lung Cancer Patients Treated with ICIs: Development and Preliminary Application of a Dual-Driver Intervention Strategy

Multidimensional Frailty-Symptom Interaction Mechanisms in Lung Cancer Patients Treated with ICIs: Development and Preliminary Application of a Dual-Driver Intervention Strategy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110412
Enrollment
Unknown
Registered
2025-10-13
Start date
2025-10-13
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

Lung cancer patients receiving immune checkpoint inhibitor therapy group:none
Intervention group( Lung cancer patients receiving immune checkpoint inhibitor therapy):Based on routine diagnosis, treatment, and nursing measures, a multidisciplinary management team is established.
Control group( Lung cancer patients receiving immune checkpoint inhibitor therapy):Receive routine clinical diagnosis, treatment, and nursing care, including health education and the distribution of t

Sponsors

The Second Affiliated Hospital of Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Diagnosed with primary lung cancer by organized pathology or cytology; 2. Treatment regimen based on immune checkpoint inhibitors (ICIs); 3. Age >= 18 years; 4. Patients clearly understand their condition and agree to participate in this study and follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients with critical conditions who cannot continue treatment; 2. Those with concurrent failure of other organs such as liver and kidneys; 3. Those with concurrent other malignant tumors; 4. Vulnerable groups such as patients with mental illnesses, cognitive impairments, Alzheimer’s disease or other dementias, pregnant women, and disabled individuals; 5. Patients currently participating in interventional studies.

Design outcomes

Primary

MeasureTime frame
Basic Information;Laboratory Test Parameters;Multidimensional Frailty;symptoms;Immune-related Adverse Events;Quality of life;

Countries

China

Contacts

Public ContactFeng Xiuqin

The Second Affiliated Hospital of Zhejiang University School of Medicine

fengxiuqin@zju.edu.cn+86 137 5711 9151

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026