Intracranial malignant tumor
Conditions
Interventions
Trial Group:Functional neuro-navigation combined with intraoperative fluorescein sodium and intraoperative ultrasound
Control group:Functional neuro-navigation
Sponsors
Inner Mongolia Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. None of them had received radiotherapy or chemotherapy before the operation. 2. Before the operation, they had no unconsciousness and were able to cooperate with the examination. 3.Through imaging examinations, the tumor was located above the tentorium cerebelli. 4.The first surgery was performed and the pathological diagnosis was intracranial malignant tumor (grade ? - ?).
Exclusion criteria
Exclusion criteria: 1. Those with severe heart, liver, kidney or other major diseases. 2. Those who cannot tolerate enhanced examinations. 3.Those with a history of cerebral hemorrhage, extensive cerebral infarction or other intracranial occupying lesions in the past. 4.Those who are allergic to sodium fluorescein. 5.Pregnant women and other patients who cannot undergo surgical treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor resection rate;Extent of tumor resection;Tumor volume;Functional improvement (including comparison of changes in functional impairment based on KPS score between preoperative and 3-month postoperative periods, and comparison of changes in muscle strength from preoperative to discharge between the two groups).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression free survival (PFS);New-onset neurological deficit;Postoperative complications (including observation for epilepsy, intracranial infection, and pulmonary infection).;Surgery time; | — |
Countries
China
Contacts
Public ContactWang Zhong
Inner Mongolia Autonomous Region People's Hospital
Outcome results
None listed