Skip to content

Clinical evaluation of the anesthetic efficacy and safety of 0.4% preservative-free obucaine hydrochloride eye drops for phacoemulsification cataract surgery

Clinical evaluation of the anesthetic efficacy and safety of 0.4% preservative-free obucaine hydrochloride eye drops for phacoemulsification cataract surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500110360
Enrollment
Unknown
Registered
2025-10-13
Start date
2025-10-13
Completion date
Unknown
Last updated
2025-10-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract

Interventions

Experimental Group:4% preservative-free obucaine hydrochloride eye drops were applied to the operated eye every 5 minutes before the operation for a total of 3 times of surface anesthesia

Sponsors

The Fourth Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >18 years old; 2. Best corrected visual acuity <0.5; 3. Lens opacity; 4. Senile cataract patients with nuclear opacity grade II-III; 5. Meet the surgical indications for phacoemulsification; 6. Be able and willing to participate in the relevant questionnaires and examinations of the trial, and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with complicated cataract combined with other eye diseases were excluded; 2. Patients with systemic infection and rheumatic diseases were excluded; 3. Patients with active ocular infection such as dacryocystitis, conjunctivitis and keratitis were excluded; 4. Patients with previous allergy to general anesthesia or topical anesthetics were excluded. 5. Patients with corneal endothelial cell count less than 1000 were excluded. 6. Patients with glaucoma and pterygium were excluded. 7. Pregnant women drink lactating women, or women who became pregnant during the study period.

Design outcomes

Primary

MeasureTime frame
Visual virtual scale score;

Secondary

MeasureTime frame
Numerical rating scale score;Verbal description rating Scale score;Results of the Wong-Baker facial Expression pain assessment questionnaire;Visual acuity;Intraocular pressure;

Countries

China

Contacts

Public ContactJiangyue Zhao

The Fourth Affiliated Hospital of China Medical University

jyzhao@cmu.edu.cn+86 24 6203 5015

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026